Peptide Synthesizer

Peptide Synthesizer

Peptide Synthesizer

Specialized peptide synthesizer for automated peptide synthesis.

Peptide Synthesizer Overview

The Peptide Synthesizer is a glass/automated reactor platform for solid-phase peptide synthesis (SPPS). It typically comprises a reaction vessel with stirring, reagent feed lines, washing lines, deprotection lines, and filtration ports (often using nutsche or frit-based filtration). The system ensures precise reagent dosing, mixing, wash cycles, and solvent handling in a closed, inert environment. This unit enables repeatable peptide coupling and deprotection steps, fluid handling, and washing cycles under programmable control in research or pilot facilities.

Key Features

  • Automated peptide synthesis
  • Precise control systems
  • Borosilicate glass construction
  • High purity output

Specifications

• Reactor volumes: small to medium scale (e.g. 1 L – 50 L)

• Materials: borosilicate glass, PTFE/PEEK lines, inert joints

• Operating pressure: often slight vacuum or inert gas atmosphere

• Temperature: ambient to ~80 °C (typical SPPS conditions)

• Agitation: magnetic or mechanical stirrer

• Ports: multiple reagent, solvent, wash lines and valves

• Filtration: integrated frit or nutsche filtration interface

• Control: programmable reagent dosing, timing, and sequence automation

• Features: inert gas purge, sealing closures, reagent reservoirs, wash/waste lines

Applications

• Solid-phase peptide synthesis (SPPS) for research and scale-up

• Production of peptide intermediates and small peptides

• Synthesis of peptide libraries and custom peptide sequences

• Biochemistry, pharmaceutical R&D, and specialty chemical synthesis

• Automation of coupling, deprotection, and wash cycles

Its precise control over reaction and wash steps, combined with automated sequencing, makes it a key tool in peptide development workflows.

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